Sevilla coach Vincenzo Montella has suggested that the only way his side will be able to stop Manchester United forward Alexis Sanchez in Wednesday's Champions League last-16 first leg will be to tie the Chilean up with a rope.
Jose Mourinho's side have been the most impressive of any of the title contenders.
Media reports said former England manager Roy Hodgson was in line to replace De Boer at Selhurst Park.
News of all that's transpired on and off the football field
Alexis Sanchez is facing a crucial period to justify his big-money wages at Old Trafford.
Top-class goals from Bernardo Silva and Sergio Aguero took Manchester City back to the top of the Premier League in a 2-0 win over Fulham at Craven Cottage on Saturday.
With United unable to sign a replacement, the pressure will be on 21-year-old England forward Marcus Rashford to deliver the goals in a more central role than he has previously operated in.
A last-minute own goal gave Liverpool a 2-1 win over Tottenham Hotspur to keep them top of the Premier League but Manchester City stayed two points behind having won at Fulham. Huddersfield Town were relegated after their defeat by Crystal Palace.
'Next season will be better for him, but he is learning how to play with us and we are learning how to get the best out of him'
Tottenham Hotspur routed Bournemouth 5-0 as they leapfrogged City into second place in the league, six points behind leaders Liverpool who thrashed Newcastle United 4-0.
Five talking-points from the Premier League weekend after Manchester United extended their winning run against Tottenham Hotspur, Liverpool were made to work hard for their win at Brighton & Hove Albion and Arsenal losing at West Ham United.
Images from the English Premier League matches played on Saturday
Tottenham Hotspur have shown impressive durability in the Premier League lately, but they will need to be at their most steadfast to deny champions and league leaders Manchester City who travel to Wembley on Monday.
Wes Morgan's 90th-minute header earned 10-man Leicester City a 2-1 victory over relegation-threatened Burnley at Turf Moor in the Premier League on Saturday.
Saturday's clash between Manchester United and Tottenham Hotspur at Old Trafford is already shaping up as an early-season eliminator to challenge runaway leaders Manchester City for the Premier League title.
Arsenal's new manager Unai Emery faces a baptism of fire after the Gunners were handed an opening day fixture at home to Premier League champions Manchester City.
League One Burton, managed by Nigel Clough, the son of former Nottingham Forest boss Brian, must endure another 90 minutes at their own ground on Jan. 23 before City formally book their place in the final.
Leeds United returned to the Premier League after a 16-year absence on Friday as West Bromwich Albion's loss at Huddersfield Town guaranteed them a top-two finish in the Championship. Three times English champions, Leeds were relegated from the Premier League in 2004 after hitting financial trouble and being forced to sell a host of big-name players such as Robbie Keane, Jonathan Woodgate and Lee Bowyer.
IMAGES from the English Premier League match played on Saturday
Romelu Lukaku scored for Chelsea in a 5-1 FA Cup third-round victory
There will be no seismic shifts in the balance of the world's richest football competition if the first weekend of the new Premier League season is anything to go by.
Chelsea manager Maurizio Sarri made a winning start to life in the Premier League as his team enjoyed a 3-0 win over Huddersfield Town at the John Smith's Stadium on Saturday.
Manchester City paid the price for missed chances as they were held to a 1-1 draw at Burnley on Saturday with Johann Berg Gudmundsson's 82nd minute equaliser earning the hosts a share of the points.
Second-tier Forest's buoyant fans were briefly silenced when Leicester grabbed a lifeline before halftime as Kelechi Iheanacho pounced on an error to score from an acute angle.
Last season's FA Cup runners-up Chelsea struck four times before the break to crush second-tier Hull City 4-0 and stroll into the quarter-finals at Stamford Bridge on Friday.
71-year-old Sven-Goran Eriksson won 18 trophies with various clubs in Sweden, Portugal and Italy, between 1979 and 2000, and became the first manager to win league-and-cup doubles in three countries.
A preview of the line-up action in the English Premier League
IMAGES from the English Premier League matches played on Saturday
Manchester City emerged from a trough of despair to beat Tottenham Hotspur 3-1 and move to within three points of the Premier League title at Wembley on Saturday.
News of all that's transpired on and off the football field
A Roberto Firmino hat-trick proved the highlight of Liverpool's 5-1 demolition of Arsenal as the Premier League leaders opened a nine-point gap over Tottenham Hotspur, who lost 3-1 to Wolverhampton Wanderers.
Manchester City soared above the fog swirling round the Etihad Stadium to demolish Tottenham Hotspur 4-1 and leave the rest of the Premier League peering into the distance in search of Pep Guardiola's record-breaking team on Saturday.
City are two points behind leaders Liverpool, but have a game in hand
Manchester City stayed ahead of age-old local rivals Manchester United at the top of the Premier League on Saturday with a deserved 1-0 win away to champions Chelsea.
City will look to extend lead against United at Old Trafford
News of all that's transpired on and off the football field
Manchester City opened up a two-point lead over their neighbours Manchester United at the top of the English Premier League on Saturday thanks to another display of scintillating brilliance in a 7-2 thrashing of Stoke City at the Etihad Stadium.
Substitute Jesse Lingard struck twice in the second half as Manchester United fought back from 2-0 down to earn a 2-2 Premier League draw with Burnley at Old Trafford on Tuesday.
Brian McDermott remains Leeds United manager but admits his future remains unclear after three days of upheaval at the Championship club.
Images from the English Premier League matches played on Tuesday.
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